physical abuse history linked to fibroids in premenopausal women
new US study has found that both physical and sexual abuse history are associated with higher incidence of uterine fibroids
later in life.
leiomyomas, also known as fibroids or myomas, are benign, hormone-dependent tumors that are clinically symptomatic in significant
number of reproductive age women.
in the study included 68,505 premenopausal nurses and Sixty-five percent of these women reported physical or sexual abuse
as a child or teen.
researchers discovered 9,823 incident diagnoses of ultrasound- or hysterectomy confirmed uterine leiomyomas and risk for fibroids
increased from eight to 36 percent among those with the mildest to most severe cumulative abuse in childhood.
analyses showed that exposure to physical, sexual or emotional abuse in childhood and adolescence was associated with an increased
risk for clinically symptomatic fibroid tumors in adulthood. The impact of early life adversity on fibroid risk persisted
even among those with no future violence exposure in adulthood," said lead author Renee Boynton Jarrett.
addition, the researchers found having a consistent emotionally supportive relationship in childhood was protective when included
as a covariate in the multivariate model of cumulative violence predicting leiomyoma.
to Boynton-Jarrett, early life exposure to violence may underpin biologic and behavioral patterns that affect fibroid risk
findings appeared in the journal Epidemiology. (ANI)